Install Hail on a Spark Cluster
If you are using Google Dataproc, please see these simpler instructions. If you are using Azure HDInsight please see these simpler instructions.
Hail should work with any Spark 3.5.x cluster built with Scala 2.12.
Hail needs to be built from source on the leader node. Building Hail from source requires:
Java 11 JDK.
Python 3.9 or later.
A recent C and a C++ compiler, GCC 5.0, LLVM 3.4, or later versions of either suffice.
The LZ4 library.
BLAS and LAPACK.
On a Debian-like system, the following should suffice:
apt-get update
apt-get install \
openjdk-11-jdk-headless \
g++ \
python3 python3-pip \
libopenblas-dev liblapack-dev \
liblz4-dev
The next block of commands downloads, builds, and installs Hail from source.
git clone https://github.com/hail-is/hail.git
cd hail/hail
make install-on-cluster HAIL_COMPILE_NATIVES=1 SCALA_VERSION=2.12.18 SPARK_VERSION=3.5.0
If you forget to install any of the requirements before running make install-on-cluster, it’s possible to get into a bad state where make insists you don’t have a requirement that you have in fact installed. Try doing make clean and then a fresh invocation of the make install-on-cluster line if this happens.
On every worker node of the cluster, you must install a BLAS and LAPACK library such as the Intel MKL or OpenBLAS. On a Debian-like system you might try the following on every worker node.
apt-get install libopenblas liblapack3
Hail is now installed! You can use ipython
, python
, and jupyter
notebook
without any further configuration. We recommend against using the
pyspark
command.
Let’s take Hail for a spin! Create a file called “hail-script.py” and place the following analysis of a randomly generated dataset with five-hundred samples and half-a-million variants.
import hail as hl
mt = hl.balding_nichols_model(n_populations=3,
n_samples=500,
n_variants=500_000,
n_partitions=32)
mt = mt.annotate_cols(drinks_coffee = hl.rand_bool(0.33))
gwas = hl.linear_regression_rows(y=mt.drinks_coffee,
x=mt.GT.n_alt_alleles(),
covariates=[1.0])
gwas.order_by(gwas.p_value).show(25)
Run the script and wait for the results. You should not have to wait more than a minute.
python3 hail-script.py
Slightly more configuration is necessary to spark-submit
a Hail script:
HAIL_HOME=$(pip3 show hail | grep Location | awk -F' ' '{print $2 "/hail"}')
spark-submit \
--jars $HAIL_HOME/hail-all-spark.jar \
--conf spark.driver.extraClassPath=$HAIL_HOME/hail-all-spark.jar \
--conf spark.executor.extraClassPath=./hail-all-spark.jar \
--conf spark.serializer=org.apache.spark.serializer.KryoSerializer \
--conf spark.kryo.registrator=is.hail.kryo.HailKryoRegistrator \
hail-script.py
Next Steps
Get the Hail cheatsheets
Follow the Hail GWAS Tutorial